Frequency and enzyme activity of the butyrylcholinesterase K-variant in a Turkish population
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, cilt.59, sa.12, ss.875-877, 2004 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 59 Sayı: 12
- Basım Tarihi: 2004
- Doi Numarası: 10.1007/s00228-003-0716-x
- Dergi Adı: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.875-877
- Hacettepe Üniversitesi Adresli: Evet
Özet
Objective. Among variants of the butyrylcholinesterase gene (BChE), the K-variant causing Ala539Thr substitution is the most common one associated with about one-third reduction in the enzyme activity. This study aimed to detect the frequency of the K-variant allele in a Turkish population sample and also to evaluate how the plasma BChE activity was influenced by this variant.