Reduced irisin levels in patients with acromegaly
HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION, cilt.43, sa.3, ss.251-261, 2022 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 43 Sayı: 3
- Basım Tarihi: 2022
- Doi Numarası: 10.1515/hmbci-2022-0009
- Dergi Adı: HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, Chemical Abstracts Core, EMBASE, MEDLINE
- Sayfa Sayıları: ss.251-261
- Anahtar Kelimeler: acromegaly, FNDC5 polymorphism, irisin, somatostatin receptor ligand, ADIPOSE-TISSUE, DIABETES-MELLITUS, FNDC5, METABOLISM, GLUCOSE, GENE, CONSENSUS, CRITERIA, SERUM, CURE
- Hacettepe Üniversitesi Adresli: Evet
Özet
Objectives: Several metabolic disturbances are seen in acromegaly however, data regarding the contribution of irisin to these disturbances is currently insufficient. In a cohort of patients with acromegaly, we measured serum irisin levels in active and controlled cases and determined independent factors that effect serum irisin including fibronectin type III domain-containing protein 5 (FNDC5) genotyping.