Lycopene sensitizes the cervical cancer cells to cisplatin via targeting nuclear factor- kappa B (NF-κB) pathway

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Aktepe O. H., Şahin T. K., Güner G., Arik Z., Yalçin Ş.

Turkish journal of medical sciences, cilt.51, ss.368-374, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51
  • Basım Tarihi: 2021
  • Doi Numarası: 10.3906/sag-2005-413
  • Dergi Adı: Turkish journal of medical sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.368-374
  • Anahtar Kelimeler: Lycopene, cervix cancer, cancer treatment, chemotherapy, BREAST-CANCER, NRF2, INHIBITION, RESISTANCE, APOPTOSIS, EXPRESSION, SURVIVAL
  • Hacettepe Üniversitesi Adresli: Hayır

Özet

Background/aim: Lycopene is associated with anticancer effects in various tumor types. However, the exact underlying mechanisms of action of lycopene in human cervical cancer remain to be determined. This study aimed to determine anticancer efficacy and mechanism of lycopene in human cervical carcinoma (HeLa) cells.