Early stroke risk and ABCD2 score performance in tissue- vs time-defined TIA A multicenter study

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Giles M. F., Albers G. W., AMARENCO P., Arsava E. M., ASIMOS A. W., Ay H., ...More

NEUROLOGY, vol.77, no.13, pp.1222-1228, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 77 Issue: 13
  • Publication Date: 2011
  • Doi Number: 10.1212/wnl.0b013e3182309f91
  • Journal Name: NEUROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1222-1228
  • Hacettepe University Affiliated: Yes


Objectives: Stroke risk immediately after TIA defined by time-based criteria is high, and prognostic scores (ABCD2 and ABCD3-I) have been developed to assist management. The American Stroke Association has proposed changing the criteria for the distinction between TIA and stroke from time-based to tissue-based. Research using these definitions is lacking. In a multicenter observational cohort study, we have investigated prognosis and performance of the ABCD2 score in TIA, subcategorized as tissue-positive or tissue-negative on diffusion-weighted imaging (DWI) or CT imaging according to the newly proposed criteria.