Molecularly Imprinted Cryogels for Human Serum Albumin Depletion

Andac, AYŞE; Galaev, Igor; Yavuz, HANDAN; DENİZLİ, ADİL

doi:10.1007/978-1-4939-2447-9_19

Molecularly Imprinted Cryogels for Human Serum Albumin Depletion

Atıf İçin Kopyala

Andac M., Galaev I. Y., Yavuz H., DENİZLİ A.

AFFINITY CHROMATOGRAPHY: METHODS AND PROTOCOLS, 3RD EDITION, cilt.1286, ss.233-237, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 1286
Basım Tarihi: 2015
Doi Numarası: 10.1007/978-1-4939-2447-9_19
Dergi Adı: AFFINITY CHROMATOGRAPHY: METHODS AND PROTOCOLS, 3RD EDITION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.233-237
Hacettepe Üniversitesi Adresli: Evet

Özet

Molecularly imprinted polymers can be used for the selective capture of a target molecule from complex medium. Cryogels novel matrices, which characterized by their supermacropores that makes their use advantageous when studying with biological samples. By combining high selectivity of the molecular imprinting approach with using cryogel as a base polymer, in this protocol, preparation of the albumin-imprinted cryogels is described. This material is a useful candidate for the selective albumin depletion from the human serum sample prior to the detailed proteomic analysis.