Relationship of PON2 gene Ser311Cys polymorphism and serum paraoxonase activity with coronary artery disease in Turkish population

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Atıf İçin Kopyala

Bayrak T., Bayrak A., VOLKAN SALANCI B., Deniz A., TOKGÖZOĞLU S. L., YAVUZ B., ...Daha Fazla

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.37, sa.2, ss.150-155, 2012 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 37 Sayı: 2
• Basım Tarihi: 2012
• Doi Numarası: 10.5505/tjb.2012.58066
• Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.150-155
• Hacettepe Üniversitesi Adresli: Evet

Özet

Objective: Paraoxonase-2 (PON2) is a cellular enzyme that has antioxidant properties similar to PON1, an HDL-associated serum enzyme playing an important role in the prevention of atherosclerosis. 1. The aim of this study is to investigate whether serum paraoxonase activity and PON2 Ser311Cys polymorphism are related to coronary artery disease and the extent of atherosclerosis.