AMERICAN JOURNAL OF SPORTS MEDICINE, 2022 (Peer-Reviewed Journal)
Article / Article
AMERICAN JOURNAL OF SPORTS MEDICINE
Science Citation Index Expanded, Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EBSCO Education Source, Education Abstracts, EMBASE, MEDLINE, SportDiscus
Achilles tendon, TGF-beta 3, PLGA-b-PEG, nanoparticle, TGF-BETA, GENE-EXPRESSION, STEM-CELLS, REPAIR, CHITOSAN, RUPTURE, MATRIX, DIFFERENTIATION, TISSUE, CHONDROGENESIS
Background: Achilles tendon (AT) midsubstance injuries may heal suboptimally, especially in athletes. Transforming growth factor-beta 3 (TGF-beta 3) shows promise because of its recently discovered tendinogenic effects. Using poly(lactic-co-glycolic acid)-b-poly(ethylene glycol) (PLGA-b-PEG) nanoparticles (NPs) may enhance the results by a sustained-release effect.