[Relationship Between Alcohol Dependence and Neuropeptide Y (NPY) Gene Promoter Polymorphisms in A Turkish Sample].


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Akel Bilgiç H., Gürel Ş. C. , Ayhan Y., Karahan S., Karakaya İ., Babaoğlu M., ...More

Turk psikiyatri dergisi = Turkish journal of psychiatry, vol.31, no.4, pp.232-238, 2020 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.5080/u25044
  • Journal Name: Turk psikiyatri dergisi = Turkish journal of psychiatry
  • Journal Indexes: Social Sciences Citation Index, Scopus, Central & Eastern European Academic Source (CEEAS), EMBASE, MEDLINE, Psycinfo, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.232-238
  • Keywords: Alcoholism, genetics, NPY, polymorphism, NATIONAL EPIDEMIOLOGIC SURVEY, GENOME-WIDE ASSOCIATION, SINGLE NUCLEOTIDE POLYMORPHISM, POPULATION-BASED SAMPLE, ENVIRONMENTAL CONTRIBUTIONS, MAJOR DEPRESSION, ANXIETY DISORDERS, RISK, EXPRESSION, SUBSTANCE

Abstract

Objective: Neuropeptide Y (NPY) is a protein widely expressed in the central nervous system and involved in diverse physiological processes, such as emotional regulation, nutritional behavior, and stress. In some populations, studies on alcohol dependence (AD) and the NPY gene have found that NPY variations increase alcohol consumption and thus may potentially be associated with AD. In this study, we investigated the relationship between NPY gene promoter polymorphisms and phenotypes related to alcohol use.