[Relationship Between Alcohol Dependence and Neuropeptide Y (NPY) Gene Promoter Polymorphisms in A Turkish Sample].

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Akel Bilgiç H., Gürel Ş. C., Ayhan Y., Karahan S., Karakaya İ., Babaoğlu M., ...Daha Fazla

Turk psikiyatri dergisi = Turkish journal of psychiatry, cilt.31, sa.4, ss.232-238, 2020 (SSCI, Scopus, TRDizin) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5080/u25044
  • Dergi Adı: Turk psikiyatri dergisi = Turkish journal of psychiatry
  • Derginin Tarandığı İndeksler: Social Sciences Citation Index (SSCI), Scopus, Central & Eastern European Academic Source (CEEAS), EMBASE, MEDLINE, Psycinfo, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.232-238
  • Anahtar Kelimeler: Alcoholism, genetics, NPY, polymorphism, NATIONAL EPIDEMIOLOGIC SURVEY, GENOME-WIDE ASSOCIATION, SINGLE NUCLEOTIDE POLYMORPHISM, POPULATION-BASED SAMPLE, ENVIRONMENTAL CONTRIBUTIONS, MAJOR DEPRESSION, ANXIETY DISORDERS, RISK, EXPRESSION, SUBSTANCE
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objective: Neuropeptide Y (NPY) is a protein widely expressed in the central nervous system and involved in diverse physiological processes, such as emotional regulation, nutritional behavior, and stress. In some populations, studies on alcohol dependence (AD) and the NPY gene have found that NPY variations increase alcohol consumption and thus may potentially be associated with AD. In this study, we investigated the relationship between NPY gene promoter polymorphisms and phenotypes related to alcohol use.