Mean platelet volume in familial Mediterranean fever related AA amyloidosis and comparison with common primary glomerular diseases


YILDIRIM T., Kutahya B., İŞ F., ERDEVİR M., ÜZERK KİBAR M., KOÇ N. S., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.51, no.5, pp.2364-2368, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 5
  • Publication Date: 2021
  • Doi Number: 10.3906/sag-2102-13
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.2364-2368
  • Keywords: AA amyloidosis, familial Mediterranean fever, glomerulonephritis, mean platelet volume, ACTIVATION, INTERLEUKIN-6, COLCHICINE, SECONDARY, CHILDREN, SIZE
  • Hacettepe University Affiliated: Yes

Abstract

Background/aim: Compared to healthy controls, mean platelet volume (MPV) is frequently higher in patients with Familial Mediterranean fever (FMF) but lower in AA amyloidosis patients. The reason for the difference in MPV levels in FMF patients with , without AA amyloidosis is unclear. The aim of the study was to determine whether low MPV is unique to AA amyloidosis or MPV is similarly low in all glomerular diseases as a result of proteinuria and/or renal dysfunction.