Antimycobacterial activity of lipodepsipeptides produced by Pseudomonas syringae. pv syringae B359


Buber E., Stindl A., Acan N. L. , Kocagoz T., Zocher R.

NATURAL PRODUCT LETTERS, vol.16, no.6, pp.419-423, 2002 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 6
  • Publication Date: 2002
  • Doi Number: 10.1080/10575630290034294
  • Journal Name: NATURAL PRODUCT LETTERS
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.419-423

Abstract

Some lipodepsipeptides produced by Pseudomonas syringae pv. syringae showed strong antimycobacterial activity towards Mycobacterium smegmatis. MIC values found were between 1.5-3.2 mug/ml, which is comparable to some primary drugs for tuberculosis. Among the lipodepsipeptides, Syringomycin E (SRE) appears to be the most potent antimycobacterial agent.