Hepatoprotective and antioxidant effects of lycopene in acute cholestasis

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Tokac M., Aydin S., Taner G., Ozkardes A. B., Yavuz Taslipinar M., DOGAN M., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.45, sa.4, ss.857-864, 2015 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3906/sag-1404-57
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.857-864
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background/aim: Lycopene, which is suggested to be a potent antioxidant, may play a protective role in diseases related to oxidative stress. In order to understand the effects of lycopene in the pathogenesis of cholestasis, we investigated the effects of lycopene on oxidative stress parameters and DNA damage induced by experimental biliary obstruction in the liver tissues and the lymphocytes of Wistar albino rats.