Pregnancy- and lactation-associated osteoporosis with severe vertebral deformities: can strontium ranelate be a new alternative for the treatment?

Tanriover M., Oz S. G., Sozen T., Kilicarslan A., Guven G. S.

Spine Journal, vol.9, no.4, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 4
  • Publication Date: 2009
  • Doi Number: 10.1016/j.spinee.2008.06.451
  • Journal Name: Spine Journal
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Bone mineral density, Lactation, Lumbar spine, Osteoporosis, Pregnancy, Strontium ranelate
  • Hacettepe University Affiliated: No

Abstract

Background context: Pregnancy- and lactation-associated osteoporosis is an uncommon condition that may be a consequence of preexisting low bone density, loss of bone mineral content during pregnancy, and increased bone turnover. Purpose: To present a case of severe osteoporosis associated with pregnancy and lactation and its treatment protocol. Study design/setting: A tertiary care hospital. Patient sample: A young female after twin pregnancy presenting with severe osteoporosis. Methods: The diagnosis was done on the basis of bone mineral density (BMD) measurement. The patient was treated with first alendronate and then strontium ranelate. She was considered as a candidate for kyphoplasty. Results: A dramatic increase in the BMD and palliation of back pain were observed. Conclusions: Strontium ranelate may be a new alternative in the treatment of pregnancy- and lactation-associated osteoporosis. © 2009 Elsevier Inc. All rights reserved.