Impact of ABO blood group incompatibility on the outcomes of allogeneic hematopoietic stem cell transplantation


Ciftciler R., GÖKER H., BÜYÜKAŞIK Y., KARAAĞAÇ AKYOL T., AKSU S., Tekin F., ...More

TRANSFUSION AND APHERESIS SCIENCE, vol.59, no.1, 2020 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.1016/j.transci.2019.06.024
  • Journal Name: TRANSFUSION AND APHERESIS SCIENCE
  • Journal Indexes: Science Citation Index Expanded, Scopus, Academic Search Premier, BIOSIS, Biotechnology Research Abstracts, EMBASE, MEDLINE

Abstract

Background and aim: ABO and Rh compatibility are not required between the donor and recipient for allogeneic hematopoietic stem cell transplantation (alloHSCT). Although ABO incompatibility is not considered a contraindication in alloHSCT, its clinical outcomes are still doubtful. In this study, we analyzed the neutrophil and platelet recovery, graft versus host disease (GVHD), relapse rate, mortality rate, non-relapse mortality and survival in patients who underwent alloHSCT.