TURKISH JOURNAL OF PHYSIOTHERAPY REHABILITATION-TURK FIZYOTERAPI VE REHABILITASYON DERGISI, sa.3, ss.290-296, 2024 (ESCI)
Purpose: Anemia is an independent factor that may influence physical functions in patients with hematological malignancy. The aim of this study was to determine the impact of anemia on physical functions in patients with hematopoietic stem cell transplantation (HSCT). Methods: A total of 82 patients with HSCT were retrospectively analyzed. The presence of anemia was determined in accordance with the WHO standard. Fatigue, hand grip and peripheral muscle strength, functional performance, and activities of daily living (ADL) were compared between patients with and without anemia. Additionally, impact of transplantation type and duration since HSCT on the results were analyzed. Results: Patients with anemia had significantly poorer quadriceps femoris muscle strength, functional performance, and ADL level than patients without anemia (p=0.025, p=0.001, and p=0.009, respectively). Additionally, the duration since HSCT were adjusted in two groups, there was still significant difference in functional performance and ADL between patients with and without anemia (p<0.05). Conclusion: The presence of anemia in patients with HSCT have negative impact on muscle strength, functional performance, and ADL level. Health care professionals should be aware that patients with anemia may have functional problems.