The efficacy of silver-embedded polypropylene-grafted polyethylene glycol-coated ventricular catheters on prevention of shunt catheter infection in rats

Hazer, Derya; Mut, MELİKE; Dincer, Nazmiye; SARIBAŞ, ZEYNEP; Hazer, Baki; Ozgen, Tuncalp

doi:10.1007/s00381-012-1729-5

The efficacy of silver-embedded polypropylene-grafted polyethylene glycol-coated ventricular catheters on prevention of shunt catheter infection in rats

Hazer D. B., Mut M., Dincer N., SARIBAŞ Z., Hazer B., Ozgen T.

CHILDS NERVOUS SYSTEM, vol.28, no.6, pp.839-846, 2012 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 28 Issue: 6
Publication Date: 2012
Doi Number: 10.1007/s00381-012-1729-5
Journal Name: CHILDS NERVOUS SYSTEM
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.839-846
Open Archive Collection: AVESIS Open Access Collection
Hacettepe University Affiliated: Yes

Abstract

Catheter-related infection is a major complication of ventriculoperitoneal shunt in children. The aim of this study is to determine inflammatory response and the efficacy of polypropylene-grafted polyethylene glycol (PP-g-PEG) copolymer and silver nanoparticle-embedded PP-g-PEG (Ag-PP-g-PEG) polymer-coated ventricular catheters on the prevention of catheter-related infections on a new experimental model of ventriculoperitoneal shunt in rats.