Bone Marrow Origin of Coronary Artery Diseases: The Impact of the Local Renin-Angiotensin System

KARAKULAK U. N., ALADAĞ KARAKULAK E., HAZNEDAROĞLU İ. C.

ACTA CARDIOLOGICA SINICA, vol.38, no.1, pp.13-20, 2022 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 38 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.6515/acs.202201_38(1).20210830a
  • Journal Name: ACTA CARDIOLOGICA SINICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, Veterinary Science Database
  • Page Numbers: pp.13-20
  • Keywords: Bone marrow, Coronary artery disease, Renin-angiotensin system, MESENCHYMAL STEM-CELLS, II TYPE-1 RECEPTOR, ATHEROSCLEROSIS, ENDOTHELIUM, EXPRESSION, DIFFERENTIATION, PROLIFERATION, ANEURYSM
  • Hacettepe University Affiliated: Yes

Abstract

The renin-angiotensin system (RAS) has both important systemic circulatory and local effects. The effects of local cardiac RAS on the cardiovascular system have been increasingly researched. In this study, we review the relationship between local bone marrow and local cardiac RAS and their impacts on atherosclerosis.