Akademik Veri Yönetim Sistemi
Cocuk Enfeksiyon Dergisi, cilt.17, sa.1, 2023 (ESCI)
Objective: The aim of this study was to investigate the clinical and laboratory findings of patients diagnosed with acute Epstein-Barr virus (EBV) infection according to age groups. Material and Methods: Patients diagnosed with acute EBV infection were enrolled in this cross-sectional study. Results: Totally, 894 patients diagnosed as acute EBV infection were included in the study. Of them, 540 (60.5%) patients were males (male/fe-male=1.52). Median age of the patients was four years (57 days-18 years). Seropositivity rate increased statistically as age increased (47.9%, 73.8% and 87.2%, respectively). Seventy patients were admitted with clinical presentation of IM with a median age of seven years (3 years-18 years). Serum median hemoglobin, leukocyte, thrombocyte, mean platelet values were statistically signficifantly different according to age groups (for all p< 0.001). Leukocytosis was more commonly encountered in EBV infected children <6 years old of age compared to 6-15 years old age and >15 years old of age (29.3%, 17.1% and 7.7%, respectively, p< 0.001). Neutro-penia was present in 157 (17.6%) patients. Mean platelet volume (MPV) increased statistically significantly as age increased (p< 0.001). MPV/platelet ratio increased significantly as age increased (p< 0.001). MPV/platelet ratio was higher in IM cases. High serum CRP was more common in <6 years old of age compared to 6-15 years old age and >15 years old of age [304 (49.4%), 204 (33.2%), 107 (17.4%), respectively, p= 0.04]. Conclusion: EBV infection causes different laboratory findings and clinical presentations according to age groups.