EFFECTS OF TIMOLOL TREATMENT ON PANCREATIC ANTIOXIDANT ENZYMES IN STREPTOZOTOCIN-INDUCED DIABETIC RATS: AN EXPERIMENTAL AND COMPUTATIONAL STUDY

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Ulusu N. N., GÖK M., Erman B., TURAN B.

JOURNAL OF MEDICAL BIOCHEMISTRY, cilt.38, sa.3, ss.306-316, 2019 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 38 Sayı: 3
• Basım Tarihi: 2019
• Doi Numarası: 10.2478/jomb-2018-0034
• Dergi Adı: JOURNAL OF MEDICAL BIOCHEMISTRY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.306-316
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• Hacettepe Üniversitesi Adresli: Evet

Özet

Background: The study aimed to investigate whether timolol-treatment has a beneficial effect on pentose phosphate pathway enzyme activities such as glucose-6-phosphate dehydrogenase (G6PD), 6-phosphogluconate dehydrogenase (6PGDH) enzyme activities and cAMP level in streptozotocin-induced diabetic rats in pancreatic tissues