Detrimental effects of nitric oxide on mesenteric circulation during endotoxaemia and its reversal by aminoguanidine
EUROPEAN JOURNAL OF SURGERY, cilt.166, sa.11, ss.888-893, 2000 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 166 Sayı: 11
- Basım Tarihi: 2000
- Doi Numarası: 10.1080/110241500447290
- Dergi Adı: EUROPEAN JOURNAL OF SURGERY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
- Sayfa Sayıları: ss.888-893
- Hacettepe Üniversitesi Adresli: Hayır
Özet
Objective: To investigate the effect of endotoxaemia on rat mesenteric vascular bed and plasma nitrite concentrations, the possible beneficial effect of aminoguanidine (the selective inducible nitric oxide synthase inhibitor) compared with N-G-nitro-L-arginine methyl ester (L-NAME) (non-selective nitric oxide synthase inhibitor).