Detrimental effects of nitric oxide on mesenteric circulation during endotoxaemia and its reversal by aminoguanidine


Yorganci K., Sayek I., Ismailoglu U., Sahin-Erdemli I.

EUROPEAN JOURNAL OF SURGERY, cilt.166, sa.11, ss.888-893, 2000 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 166 Konu: 11
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1080/110241500447290
  • Dergi Adı: EUROPEAN JOURNAL OF SURGERY
  • Sayfa Sayıları: ss.888-893

Özet

Objective: To investigate the effect of endotoxaemia on rat mesenteric vascular bed and plasma nitrite concentrations, the possible beneficial effect of aminoguanidine (the selective inducible nitric oxide synthase inhibitor) compared with N-G-nitro-L-arginine methyl ester (L-NAME) (non-selective nitric oxide synthase inhibitor).