ALOX5 promoter genotype, asthma severity and LTC4 production by eosinophils

KALAYCI Ö., Birben E., Sackesen C., KESKİN Ö., TAHAN F., WECHSLER M. E., ...Daha Fazla

ALLERGY, cilt.61, sa.1, ss.97-103, 2006 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Sayı: 1
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1111/j.1398-9995.2006.00979.x
  • Dergi Adı: ALLERGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.97-103
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: The number of Sp1-Egr1 binding tandem repeats at the ALOX5 promoter influences gene transcription and may modify the response to anti-leukotriene treatment. The relationship of ALOX5 variants to asthma severity and leukotriene production by eosinophils is unknown.