Association of prothrombin gene mutation with sepsis in a preterm with multiple intracardiac thrombi

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Cinar A., Dilber E., Karagoz T., Bahadir N., Gucer S., Tekinalp G., ...Daha Fazla

ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES, cilt.22, sa.4, ss.340-344, 2005 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 22 Sayı: 4
• Basım Tarihi: 2005
• Doi Numarası: 10.1111/j.1540-8175.2005.03107.x
• Dergi Adı: ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.340-344
• Hacettepe Üniversitesi Adresli: Evet

Özet

We report for the first time, a premature infant with multiple intracardiac thrombi and sepsis, who was heterozygous for the G20210A prothrombin gene variant. Anticoagulant treatment with low molecular weight heparin resulted in the complete disappearance of the thrombi. It may be suggested that prothrombin gene variant associated with sepsis, respiratory distress syndrome, and perinatal asphyxia, as well as other thrombophilic disorders, could be a risk factor for the development of neonatal thrombus.