Post-stroke inflammatory response is linked to volume loss in the contralateral hemisphere.
Journal of neuroimmunology, cilt.344, ss.577247, 2020 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 344
- Basım Tarihi: 2020
- Doi Numarası: 10.1016/j.jneuroim.2020.577247
- Dergi Adı: Journal of neuroimmunology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Psycinfo, Veterinary Science Database
- Sayfa Sayıları: ss.577247
- Anahtar Kelimeler: Cerebrovascular diseases, Immunology, Infections, Neuroimaging, Strokes, ISCHEMIC-STROKE, MOTOR RECOVERY, BRAIN, IMMUNE, INJURY, CLASSIFICATION, PATHOLOGY, OUTCOMES, ATROPHY, PROTEIN
- Hacettepe Üniversitesi Adresli: Evet
Özet
Objectives: There is a delicate homeostatic balance between the central nervous system and immune system. Stroke triggers an immunodepressive state to suppress a potential immune reaction directed against neuroglial tissue; however, this supposedly protective response inadvertently results in an infection-prone, and thereby a pro-inflammatory setting. In this study, we assessed the magnitude of cerebral volume loss in the unaffected contralateral hemisphere following stroke, and determined its relationship with inflammatory cascades.