Post-stroke inflammatory response is linked to volume loss in the contralateral hemisphere.


Okar S., TOPÇUOĞLU M. A. , Yemisci M. , Aktas C. , Oguz K. K. , ARSAVA E. M.

Journal of neuroimmunology, cilt.344, ss.577247, 2020 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 344
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.jneuroim.2020.577247
  • Dergi Adı: Journal of neuroimmunology
  • Sayfa Sayıları: ss.577247

Özet

Objectives: There is a delicate homeostatic balance between the central nervous system and immune system. Stroke triggers an immunodepressive state to suppress a potential immune reaction directed against neuroglial tissue; however, this supposedly protective response inadvertently results in an infection-prone, and thereby a pro-inflammatory setting. In this study, we assessed the magnitude of cerebral volume loss in the unaffected contralateral hemisphere following stroke, and determined its relationship with inflammatory cascades.