Gestation specific reference intervals for thyroid function tests in pregnancy

Akarsu S., Akbiyik F. , Karaismailoglu E. , DİKMEN Z. G.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, cilt.54, sa.8, ss.1377-1383, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 54 Konu: 8
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1515/cclm-2015-0569
  • Dergi Adı: CLINICAL CHEMISTRY AND LABORATORY MEDICINE
  • Sayfa Sayıları: ss.1377-1383

Özet

Background: Thyroid function tests are frequently assessed during pregnancy to evaluate thyroid dysfunction or to monitor pre-existing thyroid disease. However, using non-pregnant reference intervals can lead to misclassification. International guidelines recommended that institutions should calculate their own pregnancy-specific reference intervals for free thyroxine (FT4), free triiodothyronine (FT3) and thyroid-stimulating hormone (TSH). The objective of this study is to establish gestation-specific reference intervals (GRIs) for thyroid function tests in pregnant Turkish women and to compare these with the age-matched non-pregnant women.