UV Spectrophotometric Method for Determination of the Dissolution Profile of Rivaroxaban


ÇELEBİER M. , KAYNAK M. S. , ALTINÖZ S. , ŞAHİN S.

DISSOLUTION TECHNOLOGIES, cilt.21, sa.4, ss.56-59, 2014 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 21 Konu: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.14227/dt210414p56
  • Dergi Adı: DISSOLUTION TECHNOLOGIES
  • Sayfa Sayıları: ss.56-59

Özet

Rivaroxaban is an oral anticoagulant that is the first available orally active direct Factor Xa inhibitor. In this study, a UV spectrophotometric method was developed for the determination of rivaroxaban content in pharmaceutical formulations and the amount of rivaroxaban released in tablet dissolution studies. The dissolution profile of rivaroxaban was successfully determined with the validated method.