Paradoxical Air Microembolism Induces Cerebral Bioelectrical Abnormalities and Occasionally Headache in Patent Foramen Ovale Patients With Migraine

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SEVGI E. B., ERDENER Ş. E., Demirci M., TOPÇUOĞLU M. A., DALKARA T.

JOURNAL OF THE AMERICAN HEART ASSOCIATION, cilt.1, sa.6, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1161/jaha.112.001735
  • Dergi Adı: JOURNAL OF THE AMERICAN HEART ASSOCIATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: cerebral ischemia, embolism, migraine, PFO, shunts, PERCUTANEOUS CLOSURE, MECHANISMS, IMPROVEMENT, PREVALENCE, MRI
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background-Although controversial, paradoxical embolism via patent foramen ovale (PFO) may account for some of the migraine attacks in a subset of migraine with aura (MA) patients. Induction of MA attacks with air bubble injection during transcranial Doppler ultrasound in MA patients with PFO supports this view. It is likely that cerebral embolism in patients with right-to-left shunt induces bioelectrical abnormalities to initiate MA under some conditions.