The effects of non-leukoreduced red blood cell transfusions on microcirculation in mixed surgical patients

Ayhan, Banu; Yuruk, Koray; Koene, Sophia; ŞAHİN, ALTAN; Ince, Can; Aypar, Ulku

doi:10.1016/j.transci.2013.01.016

The effects of non-leukoreduced red blood cell transfusions on microcirculation in mixed surgical patients

Ayhan B., Yuruk K., Koene S., ŞAHİN A., Ince C., Aypar U.

TRANSFUSION AND APHERESIS SCIENCE, vol.49, no.2, pp.212-222, 2013 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 49 Issue: 2
Publication Date: 2013
Doi Number: 10.1016/j.transci.2013.01.016
Journal Name: TRANSFUSION AND APHERESIS SCIENCE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.212-222
Hacettepe University Affiliated: Yes

Abstract

Background: The impact of the storage process on oxygen-carrying properties of red blood cells and the efficacy of red blood cell (RBC) transfusions concerning tissue oxygenation remain an issue of debate in transfusion medicine. Storage time and leukocyte content probably interact since longer storage duration is thought to cause greater accumulation of leukocyte-derived cytokines and red blood cell injury.