TRANSFUSION AND APHERESIS SCIENCE, cilt.49, sa.2, ss.212-222, 2013 (SCI-Expanded)
Background: The impact of the storage process on oxygen-carrying properties of red blood cells and the efficacy of red blood cell (RBC) transfusions concerning tissue oxygenation remain an issue of debate in transfusion medicine. Storage time and leukocyte content probably interact since longer storage duration is thought to cause greater accumulation of leukocyte-derived cytokines and red blood cell injury.