The effects of non-leukoreduced red blood cell transfusions on microcirculation in mixed surgical patients


Ayhan B., Yuruk K., Koene S., ŞAHİN A., Ince C., Aypar U.

TRANSFUSION AND APHERESIS SCIENCE, cilt.49, sa.2, ss.212-222, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.transci.2013.01.016
  • Dergi Adı: TRANSFUSION AND APHERESIS SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.212-222
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: The impact of the storage process on oxygen-carrying properties of red blood cells and the efficacy of red blood cell (RBC) transfusions concerning tissue oxygenation remain an issue of debate in transfusion medicine. Storage time and leukocyte content probably interact since longer storage duration is thought to cause greater accumulation of leukocyte-derived cytokines and red blood cell injury.