Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health


Tsai P., Glastonbury C. A. , Eliot M. N. , Bollepalli S., YET İ. , Castillo-Fernandez J. E. , ...Daha Fazla

CLINICAL EPIGENETICS, cilt.10, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Background: Tobacco smoking is a risk factor for multiple diseases, including cardiovascular disease and diabetes. Many smoking-associated signals have been detected in the blood methylome, but the extent to which these changes are widespread to metabolically relevant tissues, and impact gene expression or metabolic health, remains unclear.