Tissue fat quantification by magnetic resonance imaging: proton density fat fraction in polycystic ovary syndrome


OĞUZ BAYKAL S. H., Idilman I., HELVACI N., ÇALIŞKAN GÜZELCE E., Eyupoglu D., KARÇAALTINCABA M., ...More

REPRODUCTIVE BIOMEDICINE ONLINE, vol.41, no.2, pp.329-334, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.1016/j.rbmo.2020.04.0241472-6483
  • Journal Name: REPRODUCTIVE BIOMEDICINE ONLINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Page Numbers: pp.329-334
  • Keywords: Adipose tissue, Body composition, Bone, Hyperandrogenism, MRI, Muscle, LEAN MUSCLE MASS, LIVER-DISEASE, BODY-COMPOSITION, VISCERAL FAT, WOMEN, ASSOCIATION, STEATOSIS, INOSITOL, RATHER, PCOS
  • Hacettepe University Affiliated: Yes

Abstract

Research question: What are the potential differences between lean women with and without polycystic ovary syndrome (PCOS) in fat content in liver, vertebrae, paraspinal muscles, pancreas, subcutaneous (SCAT) and visceral adipose tissue (VAT)? Magnetic resonance imaging proton density fat fraction (PDFF) was used to establish these differences. This is a novel, non-invasive, operator-independent method with comparable diagnostic sensitivity and specificity to histologic examination for fatty liver disease, and strong correlation with muscle strength in neuromuscular studies.