Vitamin D Supplementation and Prevention of Type 2 Diabetes

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AKTAŞ B. Y., Aktas O. O.

NEW ENGLAND JOURNAL OF MEDICINE, vol.381, no.18, pp.1784, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Letter
  • Volume: 381 Issue: 18
  • Publication Date: 2019
  • Doi Number: 10.1056/nejmc1912185
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1784
  • Hacettepe University Affiliated: Yes


To the Editor: In the randomized, placebo-controlled Vitamin D and Type 2 Diabetes (D2d) trial involving persons at risk for type 2 diabetes, Pittas et al. (Aug. 8 issue)(1) found that vitamin D-3 supplementation at a dose of 4000 IU per day did not result in a significantly lower risk of diabetes than placebo. Investigators emphasized that the trial was planned not only for participants with vitamin D insufficiency, given ethical considerations. Although the mean baseline vitamin D levels are well balanced between the trial groups and above insufficiency limits, more than 20% of the participants in the placebo group . . .