Effect of glutamine supplementation on diarrhea, interleukin-8 and secretory immunoglobulin a in children with acute diarrhea


YALCIN S. S. , YURDAKOK K. , TEZCAN T. , Oner L.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, cilt.38, ss.494-501, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 38 Konu: 5
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1097/00005176-200405000-00007
  • Dergi Adı: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
  • Sayfa Sayıları: ss.494-501

Özet

Objective: Glutamine is an important fuel for rapidly dividing cells such as enterocytes and lymphocytes. Exogenous glutamine supplementation in catabolic states preserves intestinal mucosal structure and function, decreases bacterial translocation, and supports normal immunologic responses. This study was planned to assess the effect of glutamine supplementation on duration and severity of diarrhea and to assess its immunomodulatory effect by measuring serum interleukin-8 (IL-8) and salivary immunoglobulin A (slgA) in children with acute diarrhea.