Effect of glutamine supplementation on diarrhea, interleukin-8 and secretory immunoglobulin a in children with acute diarrhea

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Atıf İçin Kopyala

YALCIN S. S., YURDAKOK K., TEZCAN T., Oner L.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, cilt.38, sa.5, ss.494-501, 2004 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 38 Sayı: 5
• Basım Tarihi: 2004
• Doi Numarası: 10.1097/00005176-200405000-00007
• Dergi Adı: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.494-501
• Hacettepe Üniversitesi Adresli: Evet

Özet

Objective: Glutamine is an important fuel for rapidly dividing cells such as enterocytes and lymphocytes. Exogenous glutamine supplementation in catabolic states preserves intestinal mucosal structure and function, decreases bacterial translocation, and supports normal immunologic responses. This study was planned to assess the effect of glutamine supplementation on duration and severity of diarrhea and to assess its immunomodulatory effect by measuring serum interleukin-8 (IL-8) and salivary immunoglobulin A (slgA) in children with acute diarrhea.