Association of vitamin D receptor gene polymorphisms with osteosarcoma risk and prognosis

KURUCU N., Sahin G., Sari N., Ceylaner S., Ilhan I. E.

JOURNAL OF BONE ONCOLOGY, vol.14, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14
  • Publication Date: 2019
  • Doi Number: 10.1016/j.jbo.2018.100208
  • Journal Name: JOURNAL OF BONE ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Hacettepe University Affiliated: Yes

Abstract

Objective: Through its receptor (VDR), vitamin D-3 plays an important role in a wide variety of cellular processes. Polymorphisms in VDR gene have been linked to risk of various cancers and their prognoses. We conducted a case-control study to analyze he relationship of VDR gene polymorphisms with the occurrence and prognosis of osteosarcoma.