Comparative study of receptor discordance between primary and corresponding metastatic lesions in breast cancer


Erdem G. U. , Altundag K., Ozdemir N. Y. , Sahin S., Demirci N. S. , Karatas F., ...Daha Fazla

JOURNAL OF BUON, cilt.22, sa.2, ss.365-376, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Konu: 2
  • Basım Tarihi: 2017
  • Dergi Adı: JOURNAL OF BUON
  • Sayfa Sayıları: ss.365-376

Özet

Purpose: It is well-known that tumor phenotype may change during the progression of breast cancer (BC). The purpose in this study was to compare the discordance in estrogen receptor (ER), progesterone receptor (PgR) and human epidermal growth factor receptor 2 (HER2) between primary and recurrent/metastatic lesions (RML) and also to evaluate the prognostic significance of change in tumor phenotype on survival in patients with metastatic BC.