In the crystal structure of the title Mn-II complex, [Mn(C7H4BrO2)(2)(C10H14N2O)(2)(H2O)(2)], the Mn-II cation is located on an inversion center and coordinated by two diethylnicotinamide (DENA) ligands, two 4-bromobenzoate (PBB) anions and two water molecules in a distorted octahedral geometry. The dihedral angle between the carboxylate group and the adjacent benzene ring is 3.25 (14)degrees. In the molecule, the pyridine ring and the benzene ring are oriented at a dihedral angle of 77.24 (5)degrees. In the crystal, intermolecular C-H center dot center dot center dot O hydrogen bonds link the molecules into a two-dimensional network. Weak intermolecular C-H center dot center dot center dot O hydrogen bonds and pi-pi interactions between the pyridine rings of neighbouring molecules [centroid-centroid distance = 3.537 (1) angstrom] further consolidate the crystal packing.