A new pregnane glycoside and a furostanol glycoside from Digitalis cariensis

Kirmizibekmez H., Tasdemir D., Ersoz T., Ireland C., Calis I.

PHARMAZIE, vol.57, no.10, pp.716-720, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 10
  • Publication Date: 2002
  • Journal Name: PHARMAZIE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.716-720
  • Hacettepe University Affiliated: Yes


Chemical investigation of the aerial parts of Digitalis cariensis Boiss. ex Jaub. & Spach resulted in the isolation of a new pregnane glycoside, cariensisoside (1) and a furostanol glycoside, uttroside A (2), along with the two known phenylethanoid glycosides, lugrandoside (3) and maxoside (4). On the basis of spectral (UV, IR, NMR, NIS) and chemical methods, compounds 1 and 2 were identified as digifologenin-3-O-beta-glucopyranosyl-(1-->4)-beta-oleandropyranoside and 3-O-(beta-lycotetraosyl)-26-O-(beta-glucopyranosyl)-(25R)-22alpha-methoxy-5-furostane-3beta,26-diol, respectively.