Mitochondrial transplantation methods


Kubat G. B., TÜRKEL İ., ÖZERKLİĞ B., ATALAY Ö., Suvay S., TUNCER M., ...More

in: Mitochondrial Transplantation and Transfer: Biology, Methods, Applications, and Disease, Elsevier, pp.199-214, 2024

  • Publication Type: Book Chapter / Chapter Research Book
  • Publication Date: 2024
  • Doi Number: 10.1016/b978-0-443-18858-9.00010-x
  • Publisher: Elsevier
  • Page Numbers: pp.199-214
  • Keywords: Coincubation, FluidFM, Magnetomitotransfer, Microinjection, MitoCeption, Mitochondria, MitoPunch, Pep-1, Photothermal nanoblade
  • Hacettepe University Affiliated: Yes

Abstract

Mitochondrial transplantation/transfer is a recently popular technique for modulating mitochondrial function. Mitochondrial transfer between cells has been studied in vitro and in vivo. For in vitro mitochondria transfer/transplantation, several methods are utilized and researchers develop new methods every day. The current in vitro mitochondrial transfer/transplantation methods including coincubation, microinjection, penetrating peptide (Pep-1), mitoception, photothermal nanoblade, magnetomitotransfer, MitoPunch, fluidFM, and EV mediated mitochondria transplantation/transfer will be covered in this chapter. Furthermore, we will provide the coincubation method protocol.