Protective effects of erdosteine on doxorubicin-induced hepatotoxicity in rats

YAGMURCA, Murat; BAS, Orhan; MOLLAOGLU, Hakan; SAHIN, Onder; Nacar, AHMET; KARAMAN, Ozcan; SONGUR, Ahmet

doi:10.1016/j.arcmed.2007.01.007

Protective effects of erdosteine on doxorubicin-induced hepatotoxicity in rats

YAGMURCA M., BAS O., MOLLAOGLU H., SAHIN O., Nacar A., KARAMAN O., ...Daha Fazla

ARCHIVES OF MEDICAL RESEARCH, cilt.38, sa.4, ss.380-385, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 38 Sayı: 4
Basım Tarihi: 2007
Doi Numarası: 10.1016/j.arcmed.2007.01.007
Dergi Adı: ARCHIVES OF MEDICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.380-385
Hacettepe Üniversitesi Adresli: Hayır

Özet

Background. Oxidative stress has an important role in the pathogenesis of doxorubicin-induced hepatotoxicity. The aim of this study was to investigate the hepatoprotective effects of erdosteine, an antioxidant agent, on doxorubicin-induced hepatotoxicity.