The success of the different eradication therapy regimens for Pseudomonas aeruginosa in cystic fibrosis

Emiralioglu N., YALÇIN E. E., Meral A., ŞENER B., Dogru D., Ozcelik U., ...More

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, vol.41, no.4, pp.419-423, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.1111/jcpt.12407
  • Journal Name: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.419-423
  • Keywords: cystic fibrosis, early eradication, Pseudomonas aeruginosa, treatment, YOUNG-CHILDREN, RISK-FACTORS, INFECTION, COLONIZATION, ACQUISITION, PATHOPHYSIOLOGY
  • Hacettepe University Affiliated: Yes

Abstract

What is known and objectiveAntibiotic therapy aimed at eradicating Pseudomonas aeruginosa (Pa), and improved regimens to treat chronic Pa infection have played a major role in increasing the median survival of patients with cystic fibrosis (CF). However, different clinical centres use varying eradication regimens. The aim of this study was to evaluate the efficacy of multiple eradication treatments against initial Pa infection and to determine the factors affecting the treatment success.