Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases

de Jesus, Adriana; Hou, Yangfeng; Brooks, Stephen; Malle, Louise; Biancotto, Angelique; Huang, Yan; Calvo, Katherine; Marrero, Bernadette; Moir, Susan; Oler, Andrew; Deng, Zuoming; Sanchez, Gina; Ahmed, Amina; Allenspach, Eric; Arabshahi, Bita; Behrens, Edward; Benseler, Susanne; Bezrodnik, Liliana; Bout-Tabaku, Sharon; Brescia, AnneMarie; Brown, Diane; Burnham, Jon; Soledad Caldirola, Maria; Carrasco, Ruy; Chan, Alice; Cimaz, Rolando; Dancey, Paul; Dare, Jason; DeGuzman, Marietta; Dimitriades, Victoria; Ferguson, Ian; Ferguson, Polly; Finn, Laura; Gattorno, Marco; Grom, SEZA; Hanson, Eric; Hashkes, Philip; Hedrich, Christian; Herzog, Ronit; Horneff, Gerd; Jerath, Rita; Kessler, Elizabeth; Kim, Hanna; Kingsbury, Daniel; Laxer, Ronald; Lee, Pui; Lee-Kirsch, Min; Lewandowski, Laura; Li, Suzanne; Lilleby, Vibke; Mammadova, Vafa; Moorthy, Lakshmi; Nasrullayeva, Gulnara; O'Neil, Kathleen; Onel, Karen; Ozen, SEZA; Pan, Nancy; Pillet, Pascal; Piotto, Daniela; Punaro, Marilynn; Reiff, Andreas; Reinhardt, Adam; Rider, Lisa; Rivas-Chacon, Rafael; Ronis, Tova; Roesen-Wolff, Angela; Roth, Johannes; Ruth, Natasha; Rygg, Marite; Schmeling, Heinrike; Schulert, Grant; Scott, Christiaan; Seminario, Gisella; Shulman, Andrew; Sivaraman, Vidya; Son, Mary; Stepanovskiy, Yuriy; Stringer, Elizabeth; Taber, Sara; Terreri, Maria; Tifft, Cynthia; Torgerson, Troy; Tosi, Laura; Van Royen-Kerkhof, Annet; Muskardin, Theresa; Canna, Scott; Goldbach-Mansky, Raphaela

doi:10.1172/jci129301

Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases

de Jesus A. A., Hou Y., Brooks S., Malle L., Biancotto A., Huang Y., ...Daha Fazla

JOURNAL OF CLINICAL INVESTIGATION, cilt.130, sa.4, ss.1669-1682, 2020 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 130 Sayı: 4
Basım Tarihi: 2020
Doi Numarası: 10.1172/jci129301
Dergi Adı: JOURNAL OF CLINICAL INVESTIGATION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chemical Abstracts Core, CINAHL, EMBASE, International Pharmaceutical Abstracts, MEDLINE, Veterinary Science Database
Sayfa Sayıları: ss.1669-1682
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

BACKGROUND. Undifferentiated systemic autoinflammatory diseases (USAIDs) present diagnostic and therapeutic challenges. Chronic interferon (IFN) signaling and cytokine dysregulation may identify diseases with available targeted treatments.