Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases


de Jesus A. A. , Hou Y., Brooks S., Malle L., Biancotto A., Huang Y., ...Daha Fazla

JOURNAL OF CLINICAL INVESTIGATION, cilt.130, sa.4, ss.1669-1682, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 130 Konu: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1172/jci129301
  • Dergi Adı: JOURNAL OF CLINICAL INVESTIGATION
  • Sayfa Sayıları: ss.1669-1682

Özet

BACKGROUND. Undifferentiated systemic autoinflammatory diseases (USAIDs) present diagnostic and therapeutic challenges. Chronic interferon (IFN) signaling and cytokine dysregulation may identify diseases with available targeted treatments.