Heritable components of the human fecal microbiome are associated with visceral fat

BEAUMONT M., Goodrich J. K. , JACKSON M. A. , Yet I. , Davenport E. R. , VİEİRA-SİLVA S., ...Daha Fazla

GENOME BIOLOGY, cilt.17, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier


Background: Variation in the human fecal microbiota has previously been associated with body mass index (BMI). Although obesity is a global health burden, the accumulation of abdominal visceral fat is the specific cardio-metabolic disease risk factor. Here, we explore links between the fecal microbiota and abdominal adiposity using body composition as measured by dual-energy X-ray absorptiometry in a large sample of twins from the TwinsUK cohort, comparing fecal 16S rRNA diversity profiles with six adiposity measures.