Atıf İçin Kopyala
Busby J. E., Kim S., Yazici S., Nakamura T., Kim J., He J., ...Daha Fazla
PROSTATE, cilt.66, sa.16, ss.1788-1798, 2006 (SCI-Expanded)
-
Yayın Türü:
Makale / Tam Makale
-
Cilt numarası:
66
Sayı:
16
-
Basım Tarihi:
2006
-
Doi Numarası:
10.1002/pros.20519
-
Dergi Adı:
PROSTATE
-
Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
-
Sayfa Sayıları:
ss.1788-1798
-
Anahtar Kelimeler:
prostate cancer, EGF-R and VEGF-R phosphorylation, antivascular therapy, chemotherapy resistant, angiogenesis, multidrug resistant, LYMPH-NODE METASTASIS, PHASE-II TRIAL, ANTIVASCULAR THERAPY, DUAL INHIBITION, LUNG-CANCER, EXPRESSION, ANGIOGENESIS, CARCINOMA, BLOCKADE, BONE
-
Hacettepe Üniversitesi Adresli:
Evet
Özet
BACKGROUND. Inhibiting epidermal growth factor receptor (EGF-R) and vascular endothelial growth factor receptor (VEGF-R) activation with AEE788 can decrease prostate cancer (CaP) growth/progression. We determined whether tumor cells or tumor-associated endothelial cells were the primary target by treating multidrug-resistant (MDR) CaP growing in the prostate of nude mice.