From the aerial parts of Potentilla recta, ten compounds were isolated including a neolignan glycoside (1) and nine flavonoids (2-10). The structures of the isolates were elucidated by spectroscopic properties. The presence of a neolignan glycoside in the genus Potentilla is being reported for the first time by this work. Furthermore. compounds 9 and 10 are characterized for the first time from the genus Potentilla. The chemotaxonomic importance of these compounds was also summarized. (C) 2011 Elsevier Ltd. All rights reserved.