Epigenetic approach to early-onset Parkinson's disease: low methylation status of SNCA and PARK2 promoter regions


ERYILMAZ I. E. , ÇEÇENER G., Erer S., EGELİ Ü., TUNCA B., ZARİFOĞLU M., ...Daha Fazla

NEUROLOGICAL RESEARCH, cilt.39, sa.11, ss.965-972, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 39 Konu: 11
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/01616412.2017.1368141
  • Dergi Adı: NEUROLOGICAL RESEARCH
  • Sayfa Sayıları: ss.965-972

Özet

Background and aim: The effect of epigenetic modifications in the genes related to Parkinson's disease (PD) is still unclear. In the present study, we investigated methylation status of SNCA and PARK2 genes in patients with early-onset Parkinson's disease (EOPD).