Non-Compartment and compartmental pharmacokinetics, efficacy, and safety of Kedrion FIX concentrate


Castaman G., Borchiellini A., Santagostino E., Radossi P., Aksu S., Yilmaz M., ...Daha Fazla

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.153, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 153
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.ejps.2020.105485
  • Dergi Adı: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Özet

Background: An open-label phase II, multicenter clinical trial was conducted at 11 Haemophilia Centres in Italy, Romania, and Turkey, to evaluate the pharmacokinetics (PK), efficacy, and safety of high purity, plasma-derived, double virus inactivated and double nano-filtered factor IX (pd-FIX) concentrate (Kedrion FIX), EudraCT Number: 2005-006186-14.