Non-Compartment and compartmental pharmacokinetics, efficacy, and safety of Kedrion FIX concentrate

Castaman, G.; Borchiellini, A.; Santagostino, E.; Radossi, P.; Aksu, S.; Yilmaz, M.; Serban, M.; Uscatescu, V; Truica, C.; Fasulo, M.; Mancuso, M.; Paladino, E.; Valpreda, A.; Guarnieri, C.; Macchia, R.; Scarpellini, M.; Mathew, P.; Morfini, M.

doi:10.1016/j.ejps.2020.105485

Non-Compartment and compartmental pharmacokinetics, efficacy, and safety of Kedrion FIX concentrate

Atıf İçin Kopyala

Castaman G., Borchiellini A., Santagostino E., Radossi P., Aksu S., Yilmaz M., ...Daha Fazla

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.153, 2020 (SCI İndekslerine Giren Dergi)

Cilt numarası: 153
Basım Tarihi: 2020
Doi Numarası: 10.1016/j.ejps.2020.105485
Dergi Adı: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Özet

Background: An open-label phase II, multicenter clinical trial was conducted at 11 Haemophilia Centres in Italy, Romania, and Turkey, to evaluate the pharmacokinetics (PK), efficacy, and safety of high purity, plasma-derived, double virus inactivated and double nano-filtered factor IX (pd-FIX) concentrate (Kedrion FIX), EudraCT Number: 2005-006186-14.