Neolignan, flavonoid, phenylethanoid and iridoid glycosides from Phlomis integrifolia

Saracoglu I., Varel M., Calis I., Donmez A.

TURKISH JOURNAL OF CHEMISTRY, vol.27, no.6, pp.739-747, 2003 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 6
  • Publication Date: 2003
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.739-747
  • Keywords: Phlomis integrifolia, Lamiaceae, neolignans, phenylethanoids, flavonoids, iridoids
  • Hacettepe University Affiliated: Yes


From the aerial parts of Phlomis integrifolia Hub.-Mor. (Lamiaceae) were isolated a neolignan glucoside, dehyrodiconiferyl alcohol-4-O-beta-D-glucopyranoside(1), an ester flavone glycoside chrysoeriol 7-O-(3"-O-trans-p-coumaroyl)-beta-D-glucopyranoside (2), four phenylethanoid glycosides, forsythoside B (3), verbascoside (=acteoside) (4), leucosceptoside A (5) and martynoside (6) along with an iridoid glucoside, lamiide (7). The structure elucidation of the isolated compounds was carried out by spectroscopic (UV, IR, 1D- and 2D-NMR) methods. The isolation of neolignan glucoside dehyrodiconiferyl alcohol-4-O-beta-D-glucopyranoside (1) is reported for the first time from a Phlomis species as well as for the family Lamiaceae.