Research Information System
European Spine Journal, 2026 (SCI-Expanded, Scopus)
Background: Adolescent Idiopathic Scoliosis (AIS) is a three-dimensional spinal deformity that negatively affects postural alignment, functional capacity, and quality of life. Exercise-based interventions such as Proprioceptive Neuromuscular Facilitation (PNF) and Core Stabilization (CS) are increasingly utilized to improve structural and functional outcomes in AIS, yet comparative evidence remains limited. Objective: To evaluate and compare the isolated effects of Proprioceptive Neuromuscular Facilitation (PNF) and Core Stabilization (CS) exercises on spinal curvature, trunk rotation, physical function, and health-related quality of life in adolescents with Adolescent Idiopathic Scoliosis (AIS), with the aim of informing evidence-based conservative treatment strategies. Methods: This randomized controlled trial included 52 adolescents aged 10–18 years diagnosed with AIS. Participants were randomly assigned to either a PNF group (n = 26) or a CS group (n = 26). Both groups underwent supervised exercise interventions three times per week for 10 weeks. The primary outcome was the Cobb angle. Secondary outcomes included Angle of Trunk Rotation (ATR), Scoliosis Research Society-22 (SRS-22) questionnaire scores, and physical function tests (six-minute walk test, sit-to-stand test). Assessments were conducted by blinded evaluators. Results: Both groups demonstrated significant improvements in Cobb angle, ATR, SRS-22 scores, and physical function (p < 0.05). The PNF group showed a greater reduction in Cobb angle (6.8° ± 1.2°) compared to the CS group (5.4° ± 1.1°, p < 0.05), as well as superior improvements in ATR. Quality of life and physical performance improved significantly in both groups, with no statistically significant differences between groups in SRS-22 scores. Conclusion: Both PNF and CS exercises are effective in improving spinal alignment, trunk symmetry, and physical function in adolescents with AIS. PNF appears to offer greater structural benefits, while both interventions are equally effective in enhancing quality of life. These findings support the integration of exercise-based rehabilitation into conservative management protocols for AIS.