Pericallosal Lipomas: Aetiology of Symptomatic Epilepsy or Incidental Thalamic Involvement with Idiopathic Generalized Epilepsy?: Two Case Reports

Kilic A. K. , SAYGI S.

EPILEPSI, vol.20, no.1, pp.39-42, 2014 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.5505/epilepsi.2014.92485
  • Title of Journal : EPILEPSI
  • Page Numbers: pp.39-42


Intracranial lipomas are regarded as congenital malformations of the meninx primitiva. Here we present two patients with pericallosal lipomas extending to the thalamus. They had generalized tonic-clonic seizures. Electroencephalograms showed generalized spike-wave discharges. It is known that the thalamus is important in the formation of sleep spindles and spike-wave discharges. Thalamic involvement by lipomas may play a role in the generation of generalized spike-wave discharges and epileptogenesis in these patients.