Acute Invasive Fulminant Fungal Rhinosinusitis: An Evaluation of 25 Cases
ENT UPDATES, cilt.14, sa.2, ss.42-47, 2024 (ESCI)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 14 Sayı: 2
- Basım Tarihi: 2024
- Doi Numarası: 10.5152/entupdates.2024.24396
- Dergi Adı: ENT UPDATES
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals
- Sayfa Sayıları: ss.42-47
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Hacettepe Üniversitesi Adresli: Evet
Özet
Background: Acute invasive fungal rhinosinusitis (AIFRS) is a severe infection that
affects the nasal cavity and paranasal sinuses, often seen in individuals with comor
bidities such as diabetes mellitus and hemato-oncological diseases. This study aims to
retrospectively analyze patients diagnosed with AIFRS from 2014 to 2023.
Methods: The study was a single-center, descriptive investigation focusing on demo
graphic details, clinical presentation, radio-pathological features, and suggested
management of AIFRS patients.
Results: Of the 25 patients involved in the study, with a mean age of 48 years, hemato
oncological diseases were the most common underlying condition (44%), followed by
diabetes mellitus (28%). Fungal analysis revealed Aspergillus species (32%) and Mucor
(24%). The most frequently involved site was the middle turbinate (84%), while the
least affected was the inferior turbinate (36%). The mortality rate was 48%, primar
ily due to underlying hemato-oncological diseases (32%). Aspergillus (16%) and Mucor
(16%) were the most commonly encountered pathogens in fatal cases.
Conclusion: Patients with diabetes mellitus, hemato-oncological diseases, or second
ary immunodeficiency undergoing steroid treatment should be vigilantly screened
for AIFRS. Early diagnosis and prompt management are crucial to improve patient
outcomes