Acute Invasive Fulminant Fungal Rhinosinusitis: An Evaluation of 25 Cases

Creative Commons License

Eroğlu E., Pamuk A. E., Özer S., Önerci T. M.

ENT UPDATES, vol.14, no.2, pp.42-47, 2024 (ESCI)

  • Publication Type: Article / Article
  • Volume: 14 Issue: 2
  • Publication Date: 2024
  • Doi Number: 10.5152/entupdates.2024.24396
  • Journal Name: ENT UPDATES
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals
  • Page Numbers: pp.42-47
  • Hacettepe University Affiliated: Yes

Abstract

 Background: Acute invasive fungal rhinosinusitis (AIFRS) is a severe infection that affects the nasal cavity and paranasal sinuses, often seen in individuals with comor bidities such as diabetes mellitus and hemato-oncological diseases. This study aims to retrospectively analyze patients diagnosed with AIFRS from 2014 to 2023. Methods: The study was a single-center, descriptive investigation focusing on demo graphic details, clinical presentation, radio-pathological features, and suggested management of AIFRS patients. Results: Of the 25 patients involved in the study, with a mean age of 48 years, hemato oncological diseases were the most common underlying condition (44%), followed by diabetes mellitus (28%). Fungal analysis revealed Aspergillus species (32%) and Mucor (24%). The most frequently involved site was the middle turbinate (84%), while the least affected was the inferior turbinate (36%). The mortality rate was 48%, primar ily due to underlying hemato-oncological diseases (32%). Aspergillus (16%) and Mucor (16%) were the most commonly encountered pathogens in fatal cases. Conclusion: Patients with diabetes mellitus, hemato-oncological diseases, or second ary immunodeficiency undergoing steroid treatment should be vigilantly screened for AIFRS. Early diagnosis and prompt management are crucial to improve patient outcomes