Triterpene saponins from Cyclamen mirabile and their biological activities
Journal of Natural Products, cilt.60, sa.3, ss.315-318, 1997 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 60 Sayı: 3
- Basım Tarihi: 1997
- Doi Numarası: 10.1021/np960658j
- Dergi Adı: Journal of Natural Products
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.315-318
- Hacettepe Üniversitesi Adresli: Evet
Özet
Six saponins, cyclaminorin (1), deglucocyclamin (2), cyclacoumin (3), cyclamin (4), isocyclamin (5), and mirabilin (6) were isolated from the tubers of Cyclamen mirabile. Compound 6 is a new natural compound, and its structure was established as 3-{O-β-[[β-D-xylopyranosyl-(1→2)]-[β-D- glucopyranosyl-(1→6)]-β-D-glucopyranosyl-(1→4)]-[β-D-glucopyranosyl- (1→2)]-α-L-arabinopy-ranosyl}-3β,16α,28-trihydroxyolean-12-en-30-oic acid (6). The structure elucidation of this compound was accomplished using both spectral and chemical methods. Antimicrobial and uterocontractile activities of the saponins were also investigated.