Effects of Low Dose Methotrexate in Cerebral Ischemia Reperfusion Injury in Rat


BAKAR B., Kose E. A. , Sari E., Sarkarati B., Atasoy P.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.32, sa.3, ss.507-518, 2015 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 32 Konu: 3
  • Basım Tarihi: 2015
  • Dergi Adı: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Sayfa Sayıları: ss.507-518

Özet

Background: During cerebral ischemia reperfusion injury, oxidative stress leads to excitotoxicity, blood brain barrier dysfunction and inflammation. This study was designed to evaluate possible protective effects of low dose methotrexate on cerebral transient ischemia reperfusion injury in rat.