Effects of beta-D-glucan on steroid-induced impairment of colonic anastomotic healing

Dinc S., Durmus E., Gulcelik M., Kuru B., Ustun H., Renda N., ...More

ACTA CHIRURGICA BELGICA, vol.106, no.1, pp.63-67, 2006 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 106 Issue: 1
  • Publication Date: 2006
  • Doi Number: 10.1080/00015458.2006.11679836
  • Title of Journal : ACTA CHIRURGICA BELGICA
  • Page Numbers: pp.63-67


Backgrounds/Aims : Inflammation during the early phase of anastomotic wound healing is an essential cellular response and is suppressed by corticosteroids. The anti-inflammatory effect of corticosteroids is largely responsible for its impairment of wound healing in bowel anastomosis. Beta-D-glucan, a commonly used macrophage activator, has been shown to improve anastomotic wound healing under normal conditions. In the present study, we have investigated the effects of beta-D-glucan on anastomotic wound healing in rats treated with long-term corticosteroid. 0 ID