Effects of beta-D-glucan on steroid-induced impairment of colonic anastomotic healing

Dinc S., Durmus E., Gulcelik M., Kuru B., Ustun H., Renda N., ...Daha Fazla

ACTA CHIRURGICA BELGICA, cilt.106, sa.1, ss.63-67, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 106 Konu: 1
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1080/00015458.2006.11679836
  • Sayfa Sayıları: ss.63-67


Backgrounds/Aims : Inflammation during the early phase of anastomotic wound healing is an essential cellular response and is suppressed by corticosteroids. The anti-inflammatory effect of corticosteroids is largely responsible for its impairment of wound healing in bowel anastomosis. Beta-D-glucan, a commonly used macrophage activator, has been shown to improve anastomotic wound healing under normal conditions. In the present study, we have investigated the effects of beta-D-glucan on anastomotic wound healing in rats treated with long-term corticosteroid. 0 ID